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Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α- Synucleinopathy models
Author: Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Tetrahedron Letters Publication, May 2022
Publication
New callistrilone epimers from Callistemon citrinus and their antiausterity activity against the PANC-1 human pancreatic cancer cell line
Author: A. M. Tawila, A. M. Omar, N. Duy Phan, I. Takahashi, J. Maneenet, and S. Awale
Product: Lux, Scratch Assay Module,
Kevin Gould as new Axion CEO
News
Axion BioSystems welcomes biotech industry leader Kevin Gould as new CEO
Author: Axion BioSystems
Product:
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Publication
Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors
Author: Yin Y, Rodriguez JL, Li N, Thokala R, Nasrallah MP, Hu L, Zhang L, Zhang JV, Logun MT, Kainth D, Haddad L, Zhao Y, Wu T, Johns EX, Long Y, Liang H, Qi J, Zhang X, Binder ZA, Lin Z, O'Rourke DM.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Maturation Delay of Human GABA
Publication
Maturation Delay of Human GABAergic Neurogenesis in Fragile X Syndrome Pluripotent Stem Cells
Author: Zhang A, Sokolova I, Domissy A, Davis J, Rao L, Hana Utami K, Wang Y, Hagerman RJ, Pouladi MA, Sanna P, Boland MJ, Loring JF.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Development of an in vitro potency assay of immune effector cell-mediated cytotoxicity and kinetics
Author: Sullivan D, Streeter BW, Weems OA, Chvatal SA, and Millard DC.
Product:
Alzheimers and MEA
Publication
Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability
Author: Ng B, Rowland HA, Wei T, Arunasalam K, Hayes EM, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Ffytche D, Gunn RN, Kocagoncu E, Lawson J, Malhotra PA, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Buckley NJ, Cader ZM, Lovestone S, Wade-Martins R.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
Author: Papes F, Camargo AP, de Souza JS, Carvalho VMA, Szeto RA, LaMontagne E, Teixeira JR, Avansini SH, Sánchez-Sánchez SM, Nakahara TS, Santo CN, Wu W, Yao H, Araújo BMP, Velho PENF, Haddad GG, and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Virulence factors released from Porphyromonas gingivalis induce electrophysiological dysfunction in human pluripotent stem cell-derived cardiomyocytes
Author: Heo SC, Kim YS, Kim YN, Kim JH, and Kim HJ.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
Analytical Chemistry Publication, April 2022
Publication
Bioluminescent RAPPID Sensors for the Single-Step Detection of Soluble Axl and Multiplex Analysis of Cell Surface Cancer Biomarkers
Author: E. A. van Aalen, S. F. A. Wouters, D.Verzijl, and M. Merkx
Product: Exact FL,
Identifying Seizures with MEA: Complementary Human and Rat Neuronal Models Enhance Predictivity
Poster
Identifying Seizures with MEA: Complementary Human and Rat Neuronal Models Enhance Predictivity
Author: Feng Y, Bradley J, Viatchenko-Karpinski S and Strock C.

Product: Neural Module,
A New Suite of Media for Cardiotoxicity and Drug Discovery Studies with hiPSC-Cardiomyocytes
Poster
A New Suite of Media for Cardiotoxicity and Drug Discovery Studies with hiPSC-Cardiomyocytes
Author: Armstrong A, Livingston M, Meyer N, Carlson C, Rieger C, Vaidyanathan R and Rajesh D.

Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
Development of a human derived induced pluripotent stem cell neuronal assay for early in vitro detection of seizure liability
Poster
Development of a human derived induced pluripotent stem cell neuronal assay for early in vitro detection of seizure liability
Author: Rockley KL, Roberts RA and Morton MJ
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
Identifying Seizures with MEA: Complementary Human and Rat Neuronal Models Enhance Predictivity
Poster
Electrical Impedance for Non-Destructive, Real Time Measurement of Neural Cell Viability on Microelectrode Arrays
Author: Choo S, Wallace K, Freudenrich T and Shafer T.
Product: Maestro Pro, MEA Viability Module, CytoView MEA Plate,
Publication Highlight in vitro pain assays
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Pain Research and Therapeutic Discovery
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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[DISSERTATION] TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons
Author: Hao, J.
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2022 Journal of neurosciene Methods wen publication
Publication
A defined human-specific platform for modeling neuronal network stimulation in vitro and in silico
Author: Wen J, Peitz M and Brustle O.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases
Author: Sequiera GL, Srivastava A, Sareen N, Yan W, Alagarsamy KN, Verma E, Aghanoori MR, Aliani M, Kumar A, Fernyhough P, Rockman-Greenberg C, Dhingra S.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Drug Target Review Logo
News
How to develop the next generation of CAR T-cell therapies
Author: Sarwish Rafiq, PhD
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes
Author: Wickramasinghe NM, Sachs D, Shewale B, Gonzalez DM, Dhanan-Krishnan P, Torre D, LaMarca E, Raimo S, Dariolli R, Serasinghe MN, Mayourian J, Sebra R, Beaumont K, Iyengar S, French DL, Hansen A, Eschenhagen T, Chipuk JE, Sobie EA, Jacobs A, Akbarian S, Ischiropoulos H, Ma'ayan A, Houten SM, Costa K, and Dubois NC.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,