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Drug Discovery News
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A mind for medicine
Author: Randall C. Willis
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Microglia on chimeric organoids
Publication
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids
Author: Popova G, Soliman SS, Kim CN, Keefe MG, Hennick KM, Jain S, Li T, Tejera D, Shin D, Chhun BB, McGinnis CS, Speir M, Gartner ZJ, Mehta SB, Haeussler M, Hengen KB, Ransohoff RR, Piao X, Nowakowski TJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Influence of Janus Kinase Inhibitors on the Neuronal Activity as a Proof-of-Concept Model for Itch
Author: Wohlrab J, Stintzing D, Schultz L, Jügelt K, and Schroeder OH.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Rapid Makerspace Microfabrication and Characterization of 3D Microelectrode Arrays (3D MEAs) for Organ-on-a-Chip Models
Author: Didier CM, Kundu A, and Rajaraman S.
Product:
European Biopharmaceutical review
News
Probing Models of Neurological Disease in a Dish Using Multielectrode Arrays
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Manufacturing chemist
News
Leveraging bioelectronic assays for cell-based therapy
Author: Jim Ross, Ph.D.
Product: Maestro ZHT, Impedance Module, CytoView-Z Plate, Maestro Z,
MEA viability Culture Protocol
Culture Protocol
MEA Viability Assay Protocol
Author: Axion BioSystems
Product: MEA Viability Module, CytoView MEA Plate,
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News
Studying Brains on a Lab Bench
Author: James Ross, Ph. D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
Author: Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, and Young-Pearse TL.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Kiskinis podcast on personalized medicine for neurodegenerative disorders
News
Episode #030: Using iPSCs to Discover New Therapies for Neurodegenerative Disorders with Professor Evangelos Kiskinis
Author: Evangelos Kiskinis, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
miR-29a and the PTEN–GSK3β axis are involved in aluminum-induced damage to primary hippocampal neuronal networks
Author: Zhang H, Cai X, Xiang C, Han Y, and Niu Q.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
[PRE-PRINT] Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis
Author: Jovanovic VM, Malley C, Tristan CA, Ryu S, Chu P-H, Barnaeva E, Ormanoglu P, Mercado JC, Michael S, Ward ME, Simeonov A, and Singeç I.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Improved nonclinical safety profile of a novel, highly selective inhibitor of the immunoproteasome subunit LMP7 (M3258)
Author: Sloot W, Glaser N, Hansen A, Hellmann J, Jaeckel S, Johannes S, Knippel A, Lai V, and Onidi M.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Publication
Cardiotoxicity of Antineoplastic Therapies and Applications of Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Author: Huang M-F, Pang LK, Chen Y-H, Zhao R, and Lee D-F.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Publication
Cardiac toxicity from bisphenol A exposure in human-induced pluripotent stem cell-derived cardiomyocytes
Author: Hyun SA, Lee CY, Ko MY, Chon SH, Kim YJ, Seo JW, Kim KK, and Ka M.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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News
Bringing Certainty to CAR T-Cell Discovery
Author: Jim Ross
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Publication
[PRE-PRINT] Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients
Author: Li W, Luo X, Poetsch MS, Oertel R, Nichani K, Schneider M, Strano A, Hasse M, Steiner R-P, Cyganek L, Hettwer K, Uhlig S, Simon K, Guan K, and Schubert M.
Product:
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Publication
A Role for Translational Regulation by S6 Kinase and a Downstream Target in Inflammatory Pain
Author: de la Peña JB, Kunder N, Lou T-F, Chase R, Stanowick A, Barragan-Iglesias P, Pancrazio JJ, Campbell ZT.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
BioCompare
News
Choosing an Apoptosis Detection Assay
Author: Caitlin Smith, Biocompare
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Publication
Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure
Author: Chen X, Sun G, Tian E, Zhang M, Davtyan H, Beach TG, Reiman EM, Blurton-Jones M, Holtzman DM, Shi Y.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,