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Human “Heartbeats-in-a-Dish” Takes Aim at Preventing Patient Deaths from Adverse Drug-Drug Interactions
Author: Axion BioSystems
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
2016_neuroscires_isoda_robustproductionofhuman.png
Publication
Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions
Author: Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_dismodelmech_preininger_ahumanpluripotentstem.png
Publication
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
Author: Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C.
Product: Cardiac Module,
2016_jpharmacoltoxicolmethods_cavero_comprehensiveinvitroproarrhythmia.png
Publication
Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation
Author: Cavero I, Guillon JM, Ballet V, Clements M, Gerbeau JF, Holzgrefe H.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_nature_chailangkarn_ahumanneurodevelopmentalmodel.png
Publication
A human neurodevelopmental model for Williams syndrome
Author: Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_neurotoxicology_hondebrink_neurotoxicityscreeningofillicit
Publication
Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings
Author: Hondebrink L, Verboven AH, Drega WS, Schmeink S, de Groot MW, van Kleef RG, Wijnolts FM, de Groot A, Meulenbelt J, Westerink RH.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_jneurosci_yang_nav17a1632gmutation.png
Publication
Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli
Author: Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_molpsychiatry_marchetto_alteredproliferationandnetworks.png
Publication
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
Author: Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, Pierce K, Eichenfield L, Pramparo T, Eyler LT, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016 ISSCR Bader Functional characteristics of iPSC-derived neurons in MEA
Poster
Functional characterization of iPSC-derived neurons grown on micro electrode arrays (MEA) and their application to phenotypic modeling of disease models and neurotoxicity assessment in comparison to primary mouse cultures
Author: Bader BM, Jügelt K, Hess D, Kfoury E, Luerman G, Schröder OHU.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_jbiomolscreen_cotterill_characterizationofearlycortical.png
Publication
Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates
Author: Cotterill E, Hall D, Wallace K, Mundy WR, Eglen SJ, Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_jneurophysiol_newberry_developmentofaspontaneously.png
Publication
Development of a Spontaneously Active Dorsal Root Ganglia Assay using Multi-well Multielectrode Arrays
Author: Newberry K, Wang S, Hoque N, Kiss L, Ahlijanian MK, Herrington J, Graef JD.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_jamaneurol_geha_pharmacotherapyforpainin.png
Publication
Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling
Author: Geha P, Yang Y, Estacion M, Schulman BR, Tokuno H, Apkarian AV, Dib-Hajj SD, Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_methods_ho_rapidngn2inductionof.png
Publication
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
Author: Ho SM, Hartley BJ, Tcw J, Beaumont M, Stafford K, Slesinger PA, Brennand KJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_stemcellres_han_cellalignmentinducedby.png
Publication
Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation
Author: Han J, Wu Q, Xia Y, Wagner MB, Xu C.
Product: Cardiac Module,
2016_scirep_maillet_modelingdoxorubicininducedcardiotoxicity.png
Publication
Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes
Author: Maillet A, Tan K, Chai X, Sadananda SN, Mehta A, Ooi J, Hayden MR, Pouladi MA, Ghosh S, Shim W, Brunham LR.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate, Maestro Edge,
2016_neurotoxicology_johnstone_effectsofanenvironmentally.png
Publication
Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays
Author: Johnstone AF, Strickland JD, Crofton KM, Gennings C, Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_currprotoctoxicol_clements_multielectrodearraymeaassay.png
Publication
Multielectrode Array (MEA) Assay for Profiling Electrophysiological Drug Effects in Human Stem Cell-Derived Cardiomyocytes
Author: Clements M.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2016_toxicology_strickland_invitroscreeningof.png
Publication
In vitro screening of silver nanoparticles and ionic silver using neural networks yields differential effects on spontaneous activity and pharmacological responses
Author: Strickland JD, LeFew WR, Crooks J, Hall D, Ortenzio JN, Dreher K, Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_hummolgenet_vessoni_cockaynesyndromederivedneurons.png
Publication
Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony.
Author: Vessoni AT, Herai RH, Karpiak JV, Leal AM, Trujillo CA, Quinet A, Agnez Lima LF, Menck CF, Muotri AR.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_altex_tukker_isthetimeright.png
Publication
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?
Author: Tukker AM, de Groot MW, Wijnolts FM, Kasteel EE, Hondebrink L, Westerink RH.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,