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(2019) Hyvarinen et al. Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system
Publication
Co-stimulation with IL-1beta and TNF-alpha induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system
Author: Hyvärinen T, Hagman S, Ristola M, Sukki L, Veijula K, Kreutzer J, Kallio P, Narkilahti S.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
2020_journalofclinicalinvestigation_song_humanautologousipscderived
Publication
Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models
Author: Song B, Cha Y, Ko S, Jeon J, Lee N, Seo H, Park KJ, Lee IH, Lopes C, Feitosa M, Luna MJ, Jung JH, Kim J, Hwang D, Cohen BM, Teicher MH, Leblanc P, Carter BS, Kordower JH, Bolshakov VY, Kong SW, Schweitzer JS, Kim KS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
AxionBio Application Note ALS
Application Note
Amyotrophic Lateral Sclerosis (ALS)
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2020_altex_tukker_towardsanimalfreeneurotoxicity.png
Publication
Towards Animal-Free Neurotoxicity Screening: Applicability of hiPSC-Derived Neuronal Models for In Vitro Seizure Liability Assessment
Author: Tukker AM, van Kleef, RGDM, Wijnolts FMJ, de Groot, A, and Westerink RHS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
(2019) Zwartsen et al. Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings
Publication
Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings
Author: Zwartsen A, de Korte T, Nacken P, de Lange DW, Westerink RHS, Hondebrink L.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
(2019) Grijalva et al. Engineered cardiac pacemaker nodes created by TBX18 gene transfer overcome source-sink mismatch
Publication
Engineered cardiac pacemaker nodes created by TBX18 gene transfer overcome source-sink mismatch
Author: Grijalva SI, Gu J, Li J, Fernandez N, Fan J, Sung JH, Lee SY, Herndon C, Buckley EM, Park SJ, Fenton FH, Cho HC.
Product: Maestro Pro, Maestro Edge, CytoView MEA Plate, Cardiac Module,
Discover Science Magazine Video on Neural Organoids
Video
Discover Magazine Top Ten Science Achievement for 2019: Complex Neural Signals in Brain Organoids
Discover Online Magazine
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2019_actabiomater_atmaramani_rutheniumoxidebasedmicroelectrode.png
Publication
Ruthenium oxide based microelectrode arrays for in vitro and in vivo neural recording and stimulation
Author: Atmaramani R, Chakraborty B, Rihani RT, Usoro J, Hammack A, Abbott J, Nnoromele P, Black BJ, Pancrazio JJ, Cogan SF.
Product: Maestro Pro, Neural Module, Maestro Edge,
2019_stemcellres_leitner_immaturemdaneuronsameliorate.png
Publication
Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation
Author: Leitner D, Ramamoorthy M, Dejosez M, Zwaka TP.
Product: Maestro Pro, Neural Module, Maestro Edge,
2019 SfN Poster Zipperly Addiction
Poster
The role of gadd45b in striatal physiology and cocaine reward
Author: Zipperly ME, Sultan FA, Graham G-E, Simpkins NA, Savell KE, Revanna JS, Day JJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Axion Bio Poster Evoked assay neural
Poster
Evoked assay of neural circuit function with microelectrode array (MEA) technology and in vitro cell culture models
Author: Chvatal SA, Hayes HB, Nicolini AM, Arrowood CA, Millard DC.
Product: Maestro Pro, Neural Module, Lumos, CytoView MEA Plate, Maestro Edge,
2019_cardiovascres_perry_pharmacologicalactivationofikr.png
Publication
Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization
Author: Perry MD, Ng CA, Mangala MM, Ng TYM, Hines AD, Liang W, Xu MJO, Hill AP, Vandenberg JI.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
Mini brain big potential video
Product Videos
Mini brain, BIG potential
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
(2019) Miklas et al. TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
Publication
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
Author: Miklas JW, Clark E, Levy S1, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2019 SPS Poster on cardiomyocyte pacing with microelectrode array
Poster
Maturation of Human iPSC-CM Function for Improved Predictivity of in vitro Action Potential and Contractility Assays
Author: Axion BioSystems
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2019_neuropsychopharmacology_shiers_reversalofperipheralnerve.png
Publication
Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
Author: Shiers S, Mwirigi J, Pradhan G, Kume M, Black B, Barragan-Iglesias P, Moy JK, Dussor G, Pancrazio JJ, Kroener S, Price TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
AxionBio App Note Parkinsons Disease
Application Note
Parkinson's Disease
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
Poster on Concentration response evaluation to compounds for neural network function
Poster
Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function
Author: Kosnik MB, Strickland JD, Marvel SW, Wallis DJ, Wallace K, Richard AM, Reif DM, and Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
Axion MEA Plates Brochure
Product Brochure
MEA Plates - Brochure
Author: Axion BioSystems
Product: BioCircuit MEA Plate, CytoView MEA Plate, CytoView-Z Plate, Lumos OptiClear Plate, Lumos MEA Plate,
2019_plosgenet_liu_novelrolesoferstress.png
Publication
Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation
Author: Liu DC, Eagleman DE, Tsai NP.
Product: Maestro Pro, Neural Module,